Disease: Tauopathies
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VPS35 Q96QK1 VPS35 retromer complex component Transporter 0.97 0.656 0.500
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
TPO P07202 thyroid peroxidase Enzyme 1.8E-21 0.455 0.846
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
SERPINA3 P01011 serpin family A member 3 Enzyme modulator 8.8E-14 0.486 0.846
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
PPARGC1A Q9UBK2 PPARG coactivator 1 alpha Transcription factor 1.00 0.453 0.885
NR4A2 P43354 nuclear receptor subfamily 4 group A member 2 Nuclear receptor 1.00 0.529 0.846
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
MAPK8 P45983 mitogen-activated protein kinase 8 Kinase 1.00 0.397 0.885
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
HSPA4 P34932 heat shock protein family A (Hsp70) member 4 1.00 0.394 0.923
GABPA Q06546 GA binding protein transcription factor subunit alpha Transcription factor 1.00 0.379 0.885
DYRK1A Q13627 dual specificity tyrosine phosphorylation regulated kinase 1A Kinase 1.00 0.533 0.769
DNM1L O00429 dynamin 1 like Enzyme modulator 5.7E-04 0.475 0.808
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846